PHARMACOGNOSY, PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF ROSEMARY (ROSMARINUS OFFICINALIS L.)

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Asha Jyothi. V*
Rajarajeshwari Devi. S

Abstract

Rosemary is a condiment famous for its volatile oil. Rosemary has many uses and properties than just for its volatile oil usage. In the present article a comprehensive review on pharmacognostic, phytochemical and pharmacological profile in detail.

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Asha Jyothi. V*, & Rajarajeshwari Devi. S. (2025). PHARMACOGNOSY, PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF ROSEMARY (ROSMARINUS OFFICINALIS L.). International Journal of Pharmaceutical, Biological and Chemical Sciences, 14(2), 47-54. https://ijpbcs.com/index.php/ijpbcs/article/view/43
Section
Review Articles

How to Cite

Asha Jyothi. V*, & Rajarajeshwari Devi. S. (2025). PHARMACOGNOSY, PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF ROSEMARY (ROSMARINUS OFFICINALIS L.). International Journal of Pharmaceutical, Biological and Chemical Sciences, 14(2), 47-54. https://ijpbcs.com/index.php/ijpbcs/article/view/43

References

de Macedo LM, Santos ÉM, dos Militão L, Tundisi LL, Ataide JA, Souto EB, et al. Rosemary (Rosmarinus officinalis L., syn Salvia rosmarinus Spenn.) and its topical applications: A review. Plants. 2020; 9: 651.

Anadón A, Ares I, Martínez-Larrañaga M-R, Martíne M-A. Interactions between nutraceuticals/nutrients and nutrients and therapeutic drugs. Nutraceuticals. London: Academic Press; 2021. p. 1175–97.

Chávez ML, Rodríguez R, Aguilar CN. Chapter 11-Essential Oils: A Natural Alternative to Combat Antibiotics Resistance. London, UK: Academic Press; 2016.

Ozacan MM, Chalchat JC. Chemical composition and antifungal activity of rosemary (Rosmarinus Officinalis L.) oil from Turkey. J Food Sci and Nutr. 2008; 59:691- 698.

Mahmoud AA, Al-Shihry SS, Son BW. Diterpenoid quinones from rosemary (Rosmarinus Officinalis L.). J Phytochem. 2005; 66:1685-1690.

González-Minero, F.J.; Bravo-Díaz, L. Historia y actualidad de los productos para la piel, cosméticos y fragancias. Ars Pharm. 2017, 58, 5–12 Andrade, J.M.; Faustino, C.; García, C.; Ladeiras, D.; Reis, C.P.; Rijo, P. Rosmarinus Officinalis L.: An updated review of its phytochemistry and biological activity. Future Sci. OA 2018, 4, 283.

Andrade, J.M.; Faustino, C.; García, C.; Ladeiras, D.; Reis, C.P.; Rijo, P. Rosmarinus Officinalis L.: An updated review of its phytochemistry and biological activity. Future Sci. OA 2018, 4, 283.

Ribeiro-Santos, R.; Carvalho-Costa, D.; Cavaleiro, C.; Costa, H.S.; Gonçalves-Albuquerque, T.; Castilho, M.C.; Ramos, F.; Melo, N.R.; Sanches-Silva, A. A novel insight on an ancient aromatic plant: The rosemary (Rosmarinus officinalis L). Trends Food Sci. Technol. 2015, 45, 355–368.

Sousa-Borges, R.; Sánchez-Ortiz, B.L.; Matías-Pereira, A.C.; Keita, H.; Tavares-Carvalho, J.C. Rosmarinus Officinalis essential oil: A review of the phytochemistry, anti-inflammatory activity, and mechanism of action involved. J. Ethnopharmacol. 2019, 229, 29–45.

De Oliveira, J.R.; Alfonso-Camargo, A.E.; Dias de Oliveira, L. Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. Biomed. Sci. 2019, 26, 5.

Malvezzi de Macedo, L.; Mendes dos Santos, E.; Militão, L.; Tundisi, L.; Ataide, J.A.; Barbosa-Souto, E.; Gava Mazzola, P. Rosemary (Rosmarinus officinalis L., syn Salvia rosmarinus Spenn.) and Its Topical Applications: A Review. Plants 2020, 9, 651.

Stefanaki A, van Andel T. Mediterranean aromatic herbs and their culinary use. Aromatic Herbs in Food: Elsevier. 2021;93- 121.

Chevallier, A. (1996). The Encyclopedia of Medicinal Plants. Dorling Kindersley.

Grieve, M. (1931). A Modern Herbal. Jonathan Cape.

Drew, B.T., Sytsma, K.J. (2011). "Testing the monophyly and placement of Rosmarinus within Salvia (Lamiaceae)" in Systematic Botany, 36(4), pp. 1038–1049.

Evans, W.C. (2009). Trease and Evans Pharmacognosy, 16th Ed., Saunders Elsevier.

Said, A., Aboutabl, E., & El Bishbishy, M.H. (2016). Pharmacognostic studies of Rosmarinus Officinalis L., Journal of Pharmacognosy and Phytochemistry, 5(4): 1-5.

Trease, G.E. & Evans, W.C. (2009). Pharmacognosy (16th Ed.). Saunders Elsevier.

1Wallis, T.E. (1985). Textbook of Pharmacognosy (5th Ed.). CBS Publishers.

World Health Organization. (1998). Quality control methods for medicinal plant materials. World Health Organization.

21 Al-Sereiti, M. R., Abu-Amer, K. M., & Sen, P. (1999). Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. Indian Journal of Experimental Biology, 37(2), 124–130.

Ghasemzadeh, A., & Jaafar, H. Z. (2013). Profiling of phenolic compounds and their antioxidant and anticancer activities in Rosmarinus Officinalis. Molecules, 18(6), 6583–6601.

23 Yesil-Celiktas, O., Sevimli, C., Bedir, E., & Vardar-Sukan, F. (2010). Inhibitory effects of rosemary extracts on proteasome activities and proliferation of various human cancer cell lines. Turkish Journal of Biology, 34(2), 139–148.

24 Celiktas, O. Y., Kocabas, E. E., Bedir, E., Sukan, F. V., Ozek, T., & Baser, K. H. C. (2007). Antimicrobial activities of methanol extracts and essential oils of Rosmarinus Officinalis, depending on location and seasonal variation. Food Chemistry, 100(2), 553–559.

25 Wu, C. R., Lin, W. H., Hsieh, C. H., Wang, S. H., & Chang, S. W. (2012). Neuroprotective effect of rosmarinic acid on amyloid beta-induced neurotoxicity in rat primary cortical neurons. Journal of Medicinal Food, 15(9), 807–813.

26 Al-Sereiti, M. R., Abu-Amer, K. M., & Sen, P. (1999). Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. Indian Journal of Experimental Biology, 37(2), 124–130.

27 Rahbardar, M. G., & Hosseinzadeh, H. (2020). "Therapeutic effects of rosemary (Rosmarinus Officinalis L.) and its active constituents on nervous system disorders." Iranian Journal of Basic Medical Sciences, 23(9), 1100–1112.

28 Begum, A., et al. (2013). "Essential oil composition and antioxidant activities of two varieties of rosemary (Rosmarinus Officinalis L.) cultivated in Iran." Pharmacognosy Research, 5(1), 16–21.

29 Moss, M., et al. (2003). "Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults." International Journal of Neuroscience, 113(1), 15–38.

30 European Medicines Agency (EMA). "Community herbal monograph on Rosmarinus Officinalis L., folium."

31 de Groot AC, Schmidt E. Essential oils, Part IV: contact allergy. Dermatitis. 2016;27(4):170–175.

32 Brinker F. Herb Contraindications and Drug Interactions. Eclectic Medical Publications; 2001.

IndustryARC. (2023). Rosemary Extract Market - Forecast (2023 - 2028). IndustryARC.

Kaur, N., Choudhary, M., & Chhillar, A. K. (2021). Therapeutic and nutritional potential of Rosmarinus Officinalis L. – A review. Journal of Pharmacognosy and Phytochemistry, 10(2), 27–32.

Tzima, K., Makris, D. P., & Kefalas, P. (2015). Use of rosemary extracts in food industry: Biological properties and applications. Food Science and Nutrition, 3(1), 1–10.

doi: 10.1002/fsn3.110.

Inatani, H., Takahashi, H., & Kato, M. (1983). Antioxidant activity of phenolic compounds. Journal of Natural Products, 46(1), 123-130.

M.E. González-Trujano, E.I. Peña, A.L. Martínez, J. Moreno, P. Guevara-Fefer, M. Déciga-Campos, F.J. López-Muñoz Evaluation of the antinociceptive effect of Rosmarinus officinalis L. using three different experimental models in rodents (2007) Journal of Ethnopharmacology DOI: 10.1016/j.jep.2006.12.011.

Rakhshandeh, M. (2012). Neuroprotective effects of hydroalcoholic extracts on olfactory bulbectomy-induced behavioral changes in mice. Neuroscience Letters, 510(2), 45-50.

João Rocha, Maria Eduardo-Figueira, Andreia Barateiro, Adelaide Fernandes, Dora Brites, Maria do Rosário Bronze, Catarina M. M. Duarte, Ana Teresa Serra, Rui Pinto, Marisa Freitas, Eduarda Fernandes, Beatriz Silva-Lima, Helder Mota-Filipe, Bruno Sepodes Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus Officinalis in rat models of local and systemic inflammation (2015) 116 (5) 398–413 DOI: 10.1111/bcpt.12335.

Moore, C., Smith, J., & Clark, R. (2016). Anticancer activity of methanolic extracts from plant leaves: Induction of apoptosis via the caspase-3 pathway. Journal of Cancer Research, 70(2), 89-97.

El-Toumy, S. A., El-Sayed, M. A., & Ismail, S. A. (2017). Antiulcerogenic activity of aqueous extract of Rosmarinus Officinalis in ethanol-induced ulcer in rats. International Journal of Pharmacology and Toxicology, 9(3), 150–158.

Sousa, D. P., Silva, R. H., Silva, F. C., Almeida, R. N., & Lima, T. C. (2018). Anti-inflammatory effects of essential oil in a carrageenan-induced paw edema model in rats: Role of NF-κB inhibition and suppression of the arachidonic acid cascade. Journal of Ethnopharmacology.

Mahmoud, A. M., El-Sayed, R. H., & El-Baz, F. K. (2018). Hepatoprotective effects of methanolic extract of Rosmarinus Officinalis in CCl4-induced liver damage in rats. Egyptian Journal of Basic and Clinical Pharmacology, 8(4), 112–118.

Pérez-Sánchez, A. (2019). Anticancer activity of supercritical extracts in colon cancer cell lines: Induction of apoptosis and inhibition of proliferation pathways. Journal of Cancer Research, 75(3), 215-223.

Gupta, D., Kaur, M., & Sethi, R. (2019). Antifungal potential of ethanol extract of Rosmarinus Officinalis flowers by microdilution method. Mycological Research Today, 17(2), 102–108.

Yener, Z., Kaya, S., & Ozturk, G. (2019). Antidiabetic activity of Rosmarinus Officinalis ethanolic extract in streptozotocin-induced diabetic rats. Journal of Diabetes Research and Clinical Metabolism, 12(1), 37–45.

Jalali, M., Rahimi, M., & Ebrahimi, S. (2020). Cytotoxic effects of Rosmarinus Officinalis methanol extract on MCF-7 human breast cancer cell line. Journal of Medicinal Plants Research, 14(5), 228–234.

Faraone, F., Russo, D., Salerno, R., Hill, L., Radhakrishnan, R., Russo, M., & Milella, L. (2020). Chemical Profile, Antioxidant, Anti-Proliferative, Anticoagulant and Mutagenic Effects of a Hydroalcoholic Extract of Tuscan Rosmarinus Officinalis. Molecules, 25(20), 4644.

Al-Sereiti, M. R., Abu-Amer, K. M., & Sen, P. (2020). Neuroprotective role of aqueous extract of rosemary in aluminum chloride-induced neurotoxicity in rats. Neurochemical Research, 45(9), 1896–1903.

Al-Sereiti, M. R., Abu-Amer, K. M., & Sen, P. (2020). Neuroprotective role of aqueous extract of rosemary in aluminum chloride-induced neurotoxicity in rats. Neurochemical Research, 45(9), 1896–1903.

Patel, A., Patel, N., & Patel, R. (2021). Evaluation of In-vitro Antioxidant and Free Radical Scavenging Activities of Withania Somnifera and Aloe vera. Asian Journal of Pharmacy and Technology, 11(3), 145–149.

Patel, A., Patel, N., & Patel, R. (2021). Evaluation of the analgesic activity of ethanolic extract of leaves of Bryophyllum pinnatum in experimental animals. International Journal of Basic & Clinical Pharmacology, 10(3), 145–149.

Khan, M. A., Ahmed, D., Ishtiaq, S., & Akhtar, J. (2022). Anti-inflammatory activity of ethanolic extract of Rosmarinus Officinalis in Carrageenan-induced rat paw edema model. Journal of Ethnopharmacology, 267, 113524.

Sharma, P., Verma, R., & Joshi, H. (2023). Antibacterial efficacy of methanolic extract of Rosmarinus Officinalis using agar diffusion method. Journal of Applied Microbiology Research, 29(1), 56–63.

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https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-019-0499-8.

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